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BMCBI
2006
123views more  BMCBI 2006»
14 years 12 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger
BMCBI
2006
166views more  BMCBI 2006»
14 years 12 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2006
142views more  BMCBI 2006»
14 years 12 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
BMCBI
2006
113views more  BMCBI 2006»
14 years 12 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
CAD
2006
Springer
14 years 12 months ago
On visual similarity based 2D drawing retrieval
A large amount of 2D drawings have been produced in engineering fields. To reuse and share the available drawings efficiently, we propose two methods in this paper, namely 2.5D sp...
Jiantao Pu, Karthik Ramani