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149
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BMCBI
2010
121views more  BMCBI 2010»
15 years 2 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
166
Voted
BMCBI
2007
194views more  BMCBI 2007»
15 years 2 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
111
Voted
BMCBI
2007
109views more  BMCBI 2007»
15 years 2 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
113
Voted
BMCBI
2010
117views more  BMCBI 2010»
15 years 2 months ago
MetAssimulo: Simulation of Realistic NMR Metabolic Profiles
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
Harriet J. Muncey, Rebecca Jones, Maria De Iorio, ...
142
Voted
BMCBI
2007
134views more  BMCBI 2007»
15 years 2 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
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