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122
Voted
BMCBI
2008
15 years 2 months ago
2008
Background: Two problems complicate the study of selection in viral genomes: Firstly, the presence of genes in overlapping reading frames implies that selection in one reading fra...
110
Voted
BMCBI
2010
15 years 2 months ago
2010
Background: Illumina's second-generation sequencing platform is playing an increasingly prominent role in modern DNA and RNA sequencing efforts. However, rapid, simple, stand...
100
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BMCBI
2008
15 years 2 months ago
2008
Background: Cis-regulatory modules (CRMs) are distinct, genomic regions surrounding the target gene that can independently activate the promoter to drive transcription. The activa...
110
Voted
BMCBI
2007
15 years 2 months ago
2007
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
146
Voted
BMCBI
2008
15 years 2 months ago
2008
Background: Once a new genome is sequenced, one of the important questions is to determine the presence and absence of biological pathways. Analysis of biological pathways in a ge...