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BMCBI
2005
89views more  BMCBI 2005»
14 years 9 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...
BMCBI
2005
121views more  BMCBI 2005»
14 years 9 months ago
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) ma
Background: Proteomic profiling of complex biological mixtures by the ProteinChip technology of surfaceenhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectro...
Huixiao Hong, Yvonne P. Dragan, Joshua Epstein, Ca...
BMCBI
2004
208views more  BMCBI 2004»
14 years 9 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
BMCBI
2004
146views more  BMCBI 2004»
14 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2004
91views more  BMCBI 2004»
14 years 9 months ago
SIGI: score-based identification of genomic islands
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Rainer Merkl