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BMCBI
2010
137views more  BMCBI 2010»
14 years 9 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
SIGMOD
2012
ACM
224views Database» more  SIGMOD 2012»
12 years 12 months ago
Tiresias: the database oracle for how-to queries
How-To queries answer fundamental data analysis questions of the form: “How should the input change in order to achieve the desired output”. As a Reverse Data Management probl...
Alexandra Meliou, Dan Suciu
83
Voted
BMCBI
2006
123views more  BMCBI 2006»
14 years 9 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
IPSN
2004
Springer
15 years 2 months ago
Estimation from lossy sensor data: jump linear modeling and Kalman filtering
Due to constraints in cost, power, and communication, losses often arise in large sensor networks. The sensor can be modeled as an output of a linear stochastic system with random...
Alyson K. Fletcher, Sundeep Rangan, Vivek K. Goyal
79
Voted
FASE
2006
Springer
15 years 1 months ago
Argus: Online Statistical Bug Detection
Statistical debugging is a powerful technique for identifying bugs that do not violate programming rules or program invariants. Previously known statistical debugging techniques ar...
Long Fei, Kyungwoo Lee, Fei Li, Samuel P. Midkiff