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» Power and sample size estimation in microarray studies
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BMCBI
2006
86views more  BMCBI 2006»
15 years 1 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2004
150views more  BMCBI 2004»
15 years 1 months ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
105
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BMCBI
2005
126views more  BMCBI 2005»
15 years 1 months ago
An algorithm for automatic evaluation of the spot quality in two-color DNA microarray experiments
Background: Although DNA microarray technologies are very powerful for the simultaneous quantitative characterization of thousands of genes, the quality of the obtained experiment...
Eugene Novikov, Emmanuel Barillot
BMCBI
2010
165views more  BMCBI 2010»
15 years 1 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
97
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IMSCCS
2006
IEEE
15 years 7 months ago
Estimation Of Cross-Hybridization Signals Using Support Vector Regression
Microarray technology is a powerful biotechnology tool which allows researchers to simultaneously evaluate the expression of thousands of genes, if not the entire expressed genome...
Yijun Sun, Li Liu, Mick Popp, William G. Farmerie