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» Power and sample size estimation in microarray studies
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125
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BMCBI
2010
132views more  BMCBI 2010»
15 years 2 months ago
Parallel multiplicity and error discovery rate (EDR) in microarray experiments
Background: In microarray gene expression profiling experiments, differentially expressed genes (DEGs) are detected from among tens of thousands of genes on an array using statist...
Wayne Wenzhong Xu, Clay J. Carter
126
Voted
JCB
2000
103views more  JCB 2000»
15 years 1 months ago
Testing for Differentially-Expressed Genes by Maximum-Likelihood Analysis of Microarray Data
Although two-color uorescent DNA microarrays are now standard equipment in many molecular biology laboratories, methods for identifying differentially expressed genes in microarra...
Trey Ideker, Vesteinn Thorsson, Andrew F. Siegel, ...
BMCBI
2008
121views more  BMCBI 2008»
15 years 2 months ago
GeneTrailExpress: a web-based pipeline for the statistical evaluation of microarray experiments
Background: High-throughput methods that allow for measuring the expression of thousands of genes or proteins simultaneously have opened new avenues for studying biochemical proce...
Andreas Keller, Christina Backes, Maher Al-Awadhi,...
122
Voted
BMCBI
2007
163views more  BMCBI 2007»
15 years 1 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
GECCO
2004
Springer
118views Optimization» more  GECCO 2004»
15 years 7 months ago
Adaptive Sampling for Noisy Problems
Abstract. The usual approach to deal with noise present in many realworld optimization problems is to take an arbitrary number of samples of the objective function and use the samp...
Erick Cantú-Paz