243 search results - page 9 / 49 » Power and sample size estimation in microarray studies |
BMCBI
2004
14 years 9 months ago
2004
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
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BMCBI
2006
14 years 9 months ago
2006
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
BMCBI
2006
14 years 9 months ago
2006
Background: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining s...
BMCBI
2007
14 years 9 months ago
2007
Background: When conducting multiple hypothesis tests, it is important to control the number of false positives, or the False Discovery Rate (FDR). However, there is a tradeoff be...
BMCBI
2006
14 years 9 months ago
2006
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...