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BMCBI
2010
113views more  BMCBI 2010»
15 years 5 months ago
Efficient protein alignment algorithm for protein search
Background: Proteins show a great variety of 3D conformations, which can be used to infer their evolutionary relationship and to classify them into more general groups; therefore ...
Zaixin Lu, Zhiyu Zhao, Bin Fu
BMCBI
2007
94views more  BMCBI 2007»
15 years 5 months ago
Lightweight genome viewer: portable software for browsing genomics data in its chromosomal context
Background: Lightweight genome viewer (lwgv) is a web-based tool for visualization of sequence annotations in their chromosomal context. It performs most of the functions of large...
Jeremiah J. Faith, Andrew J. Olson, Timothy S. Gar...
BMCBI
2008
138views more  BMCBI 2008»
15 years 5 months ago
Information transfer in signaling pathways: A study using coupled simulated and experimental data
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...
Jürgen Pahle, Anne K. Green, C. Jane Dixon, U...
BMCBI
2010
113views more  BMCBI 2010»
15 years 5 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
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BMCBI
2007
146views more  BMCBI 2007»
15 years 5 months ago
Spatial location and its relevance for terminological inferences in bio-ontologies
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
Stefan Schulz, Kornél G. Markó, Udo ...
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