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» Practical Differential Profiling
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BMCBI
2005
116views more  BMCBI 2005»
14 years 11 months ago
Can Zipf's law be adapted to normalize microarrays?
Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
BMCBI
2005
77views more  BMCBI 2005»
14 years 11 months ago
Structural comparison of metabolic networks in selected single cell organisms
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
Dongxiao Zhu, Zhaohui S. Qin
BMCBI
2005
178views more  BMCBI 2005»
14 years 11 months ago
A quantization method based on threshold optimization for microarray short time series
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
TVCG
2008
124views more  TVCG 2008»
14 years 11 months ago
Effective visualization of complex vascular structures using a non-parametric vessel detection method
The effective visualization of vascular structures is critical for diagnosis, surgical planning as well as treatment evaluation. In recent work, we have developed an algorithm for ...
Alark Joshi, Xiaoning Qian, Donald P. Dione, Ketan...
BMCBI
2004
90views more  BMCBI 2004»
14 years 11 months ago
Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays
Background: Several aspects of microarray data analysis are dependent on identification of genes expressed at or near the limits of detection. For example, regression-based normal...
Igor Dozmorov, Nicholas Knowlton, Yuhong Tang, Mic...