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136
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BMCBI
2007
135views more  BMCBI 2007»
15 years 3 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...
143
Voted
BCB
2010
127views Bioinformatics» more  BCB 2010»
14 years 10 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
140
Voted
ISMB
1994
15 years 5 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
138
Voted
BMCBI
2006
142views more  BMCBI 2006»
15 years 3 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
129
Voted
ICSM
2009
IEEE
15 years 10 months ago
Modeling class cohesion as mixtures of latent topics
The paper proposes a new measure for the cohesion of classes in Object-Oriented software systems. It is based on the analysis of latent topics embedded in comments and identifiers...
Yixun Liu, Denys Poshyvanyk, Rudolf Ferenc, Tibor ...