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BMCBI
2008
160views more  BMCBI 2008»
15 years 5 months ago
VariVis: a visualisation toolkit for variation databases
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
Timothy D. Smith, Richard G. H. Cotton
BMCBI
2008
135views more  BMCBI 2008»
15 years 5 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...
BMCBI
2008
115views more  BMCBI 2008»
15 years 5 months ago
Probe signal correction for differential methylation hybridization experiments
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
Dustin P. Potter, Pearlly Yan, Tim Hui-Ming Huang,...
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BMCBI
2008
156views more  BMCBI 2008»
15 years 5 months ago
ArrayWiki: an enabling technology for sharing public microarray data repositories and meta-analyses
Background: A survey of microarray databases reveals that most of the repository contents and data models are heterogeneous (i.e., data obtained from different chip manufacturers)...
Todd H. Stokes, J. T. Torrance, Henry Li, May D. W...
BMCBI
2008
125views more  BMCBI 2008»
15 years 5 months ago
Tandem duplication, circular permutation, molecular adaptation: how Solanaceae resist pests via inhibitors
Background: The Potato type II (Pot II) family of proteinase inhibitors plays critical roles in the defense system of plants from Solanaceae family against pests. To better unders...
Lesheng Kong, Shoba Ranganathan
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