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BMCBI
2008
123views more  BMCBI 2008»
15 years 5 months ago
Validation of protein models by a neural network approach
Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
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BMCBI
2008
176views more  BMCBI 2008»
15 years 5 months ago
H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
Rainer Merkl, Matthias Zwick
JMLR
2006
140views more  JMLR 2006»
15 years 4 months ago
Active Learning in Approximately Linear Regression Based on Conditional Expectation of Generalization Error
The goal of active learning is to determine the locations of training input points so that the generalization error is minimized. We discuss the problem of active learning in line...
Masashi Sugiyama
JUCS
2006
225views more  JUCS 2006»
15 years 4 months ago
Restricting the View and Connecting the Dots - Dangers of a Web Search Engine Monopoly
: Everyone realizes how powerful the few big Web search engine companies have become, both in terms of financial resources due to soaring stock quotes and in terms of the still hid...
Narayanan Kulathuramaiyer, Wolf-Tilo Balke
BMCBI
2005
118views more  BMCBI 2005»
15 years 4 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz