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NAR
2008
142views more  NAR 2008»
14 years 12 months ago
CMGSDB: integrating heterogeneous Caenorhabditis elegans data sources using compositional data mining
CMGSDB (Database for Computational Modeling of Gene Silencing) is an integration of heterogeneous data sources about Caenorhabditis elegans with capabilities for compositional dat...
Amrita Pati, Ying Jin, Karsten Klage, Richard F. H...
BMCBI
2010
135views more  BMCBI 2010»
15 years 9 hour ago
Lists2Networks: Integrated analysis of gene/protein lists
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
Alexander Lachmann, Avi Ma'ayan
BMCBI
2007
96views more  BMCBI 2007»
14 years 12 months ago
Features generated for computational splice-site prediction correspond to functional elements
Background: Accurate selection of splice sites during the splicing of precursors to messenger RNA requires both relatively well-characterized signals at the splice sites and auxil...
Rezarta Islamaj Dogan, Lise Getoor, W. John Wilbur...
RECOMB
2005
Springer
16 years 6 days ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
BMCBI
2006
130views more  BMCBI 2006»
14 years 12 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...