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» Predicting Nucleolar Proteins Using Support-Vector Machines
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131
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CIBCB
2005
IEEE
15 years 5 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
ICML
2007
IEEE
16 years 4 months ago
An integrated approach to feature invention and model construction for drug activity prediction
We present a new machine learning approach for 3D-QSAR, the task of predicting binding affinities of molecules to target proteins based on 3D structure. Our approach predicts bind...
David Page, Jesse Davis, Soumya Ray, Vítor ...
132
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BMCBI
2007
113views more  BMCBI 2007»
15 years 3 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...
144
Voted
BMCBI
2007
175views more  BMCBI 2007»
15 years 3 months ago
Fast automated cell phenotype image classification
Background: The genomic revolution has led to rapid growth in sequencing of genes and proteins, and attention is now turning to the function of the encoded proteins. In this respe...
Nicholas A. Hamilton, Radosav S. Pantelic, Kelly H...
118
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PAKDD
2004
ACM
131views Data Mining» more  PAKDD 2004»
15 years 9 months ago
A Tree-Based Approach to the Discovery of Diagnostic Biomarkers for Ovarian Cancer
Computational diagnosis of cancer is a classification problem, and it has two special requirements on a learning algorithm: perfect accuracy and small number of features used in t...
Jinyan Li, Kotagiri Ramamohanarao