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» Predicting Peroxisomal Proteins
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BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
14 years 8 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung
RECOMB
2008
Springer
15 years 10 months ago
A Bayesian Approach to Protein Inference Problem in Shotgun Proteomics
The protein inference problem represents a major challenge in shotgun proteomics. Here we describe a novel Bayesian approach to address this challenge that incorporates the predict...
Yong Fuga Li, Randy J. Arnold, Yixue Li, Predrag R...
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
15 years 3 months ago
Multi-Scale Hierarchical Structure Prediction of Helical Transmembrane Proteins
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Zhong Chen, Ying Xu
BMCBI
2006
172views more  BMCBI 2006»
14 years 10 months ago
Prediction of cis/trans isomerization in proteins using PSI-BLAST profiles and secondary structure information
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
Jiangning Song, Kevin Burrage, Zheng Yuan, Thomas ...
BMCBI
2010
190views more  BMCBI 2010»
14 years 10 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...