Abstract. Given the combinatorial nature of cellular signalling pathways, where biological agents can bind and modify each other in a large number of ways, concurrent or agent-base...
In this paper, we present a solution that allows systems to remain active while they are evolving. Our approach goes out from the principle of separated concerns and has two steps....
We describe a (meta) formalism for defining a variety of (object oriented) data models in a unified framework based on a variation of first-order logic. As specific example we use...
We show how to use an interactive theorem prover, HOL, together with a model checker, SPIN, to prove key properties of distance vector routing protocols. We do three case studies: ...
Karthikeyan Bhargavan, Davor Obradovic, Carl A. Gu...
Background: CRANKITE is a suite of programs for simulating backbone conformations of polypeptides and proteins. The core of the suite is an efficient Metropolis Monte Carlo sample...