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BMCBI
2006
134views more  BMCBI 2006»
15 years 4 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BMCBI
2008
121views more  BMCBI 2008»
15 years 4 months ago
BioSAVE: Display of scored annotation within a sequence context
Background: Visualization of sequence annotation is a common feature in many bioinformatics tools. For many applications it is desirable to restrict the display of such annotation...
Richard F. Pollock, Boris Adryan
IMSCCS
2006
IEEE
15 years 10 months ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
BMCBI
2007
141views more  BMCBI 2007»
15 years 4 months ago
HeliCis: a DNA motif discovery tool for colocalized motif pairs with periodic spacing
Background: Correct temporal and spatial gene expression during metazoan development relies on combinatorial interactions between different transcription factors. As a consequence...
Erik Larsson, Per Lindahl, Petter Mostad
BMCBI
2010
160views more  BMCBI 2010»
15 years 4 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian