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BMCBI
2010
95views more  BMCBI 2010»
15 years 6 months ago
Protein structure modelling and evaluation based on a 4-distance description of side-chain interactions
Background: Accurate evaluation and modelling of residue-residue interactions within and between proteins is a key aspect of computational structure prediction including homology ...
Vladimir Potapov, Mati Cohen, Yuval Inbar, Gideon ...
BMCBI
2008
123views more  BMCBI 2008»
15 years 6 months ago
Ori-Finder: A web-based system for finding oriCs in unannotated bacterial genomes
Background: Chromosomal replication is the central event in the bacterial cell cycle. Identification of replication origins (oriCs) is necessary for almost all newly sequenced bac...
Feng Gao, Chun-Ting Zhang
CACM
2010
120views more  CACM 2010»
15 years 6 months ago
seL4: formal verification of an operating-system kernel
We report on the formal, machine-checked verification of microkernel from an abstract specification down to its C implementation. We assume correctness of compiler, assembly code,...
Gerwin Klein, June Andronick, Kevin Elphinstone, G...
BMCBI
2008
108views more  BMCBI 2008»
15 years 6 months ago
Empirical methods for controlling false positives and estimating confidence in ChIP-Seq peaks
Background: High throughput signature sequencing holds many promises, one of which is the ready identification of in vivo transcription factor binding sites, histone modifications...
David A. Nix, Samir J. Courdy, Kenneth M. Boucher
BMCBI
2008
62views more  BMCBI 2008»
15 years 6 months ago
Filtering of false positive microRNA candidates by a clustering-based approach
Background: MicroRNAs are small non-coding RNA gene products that play diversified roles from species to species. The explosive growth of microRNA researches in recent years prove...
Wing-Sze Leung, Marie C. M. Lin, David Wai-Lok Che...
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