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BIOINFORMATICS
2010
87views more  BIOINFORMATICS 2010»
15 years 3 months ago
Improving protein secondary structure prediction using a simple k-mer model
Motivation: Existing methods for protein sequence analysis are generally firstorder and inherently assume that each position is independent. We develop a general framework for int...
Martin Madera, Ryan Calmus, Grant Thiltgen, Kevin ...
BMCBI
2008
146views more  BMCBI 2008»
15 years 3 months ago
ProLoc-GO: Utilizing informative Gene Ontology terms for sequence-based prediction of protein subcellular localization
Background: Gene Ontology (GO) annotation, which describes the function of genes and gene products across species, has recently been used to predict protein subcellular and subnuc...
Wen-Lin Huang, Chun-Wei Tung, Shih-Wen Ho, Shiow-F...
109
Voted
CCE
2008
15 years 3 months ago
Prediction of secondary structures of proteins using a two-stage method
Protein structure determination and prediction has been a focal research subject in life sciences due to the importance of protein structure in understanding the biological and ch...
Fadime Üney Yüksektepe, Özlem Yilma...
101
Voted
CANDC
2006
ACM
15 years 3 months ago
Domain boundary prediction based on profile domain linker propensity index
Successful prediction of protein domain boundaries provides valuable information not only for the computational structure prediction of multidomain proteins but also for the exper...
Qiwen Dong, Xiaolong Wang, Lei Lin, Zhiming Xu
132
Voted
BMCBI
2007
113views more  BMCBI 2007»
15 years 3 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...