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BMCBI
2010
109views more  BMCBI 2010»
15 years 28 days ago
Predicting gene function using hierarchical multi-label decision tree ensembles
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
91
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BMCBI
2008
72views more  BMCBI 2008»
15 years 28 days ago
HECTAR: A method to predict subcellular targeting in heterokonts
Background: The heterokonts are a particularly interesting group of eukaryotic organisms; they include many key species of planktonic and coastal algae and several important patho...
Bernhard Gschloessl, Yann Guermeur, J. Mark Cock
118
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BMCBI
2010
133views more  BMCBI 2010»
15 years 28 days ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
90
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BMCBI
2007
94views more  BMCBI 2007»
15 years 28 days ago
False positive reduction in protein-protein interaction predictions using gene ontology annotations
Background: Many crucial cellular operations such as metabolism, signalling, and regulations are based on protein-protein interactions. However, the lack of robust protein-protein...
Mahmood A. Mahdavi, Yen-Han Lin
BMCBI
2007
134views more  BMCBI 2007»
15 years 28 days ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...