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» Predicting When Not to Predict
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140
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BMCBI
2008
102views more  BMCBI 2008»
15 years 3 months ago
Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary
Background: A number of sequence-based methods exist for protein secondary structure prediction. Protein secondary structures can also be determined experimentally from circular d...
Jonathan G. Lees, Robert W. Janes
146
Voted
BMCBI
2008
134views more  BMCBI 2008»
15 years 3 months ago
Prediction of protein-protein binding site by using core interface residue and support vector machine
Background: The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for th...
Nan Li, Zhonghua Sun, Fan Jiang
129
Voted
BMCBI
2007
105views more  BMCBI 2007»
15 years 3 months ago
Predicting RNA secondary structure by the comparative approach: how to select the homologous sequences
Background: The secondary structure of an RNA must be known before the relationship between its structure and function can be determined. One way to predict the secondary structur...
Stefan Engelen, Fariza Tahi
169
Voted
BMCBI
2008
220views more  BMCBI 2008»
15 years 3 months ago
Gene prediction in metagenomic fragments: A large scale machine learning approach
Background: Metagenomics is an approach to the characterization of microbial genomes via the direct isolation of genomic sequences from the environment without prior cultivation. ...
Katharina J. Hoff, Maike Tech, Thomas Lingner, Rol...
155
Voted
BMCBI
2008
101views more  BMCBI 2008»
15 years 3 months ago
Term-tissue specific models for prediction of gene ontology biological processes using transcriptional profiles of aging in dros
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
Wensheng Zhang, Sige Zou, Jiuzhou Song