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» Predicting When Not to Predict
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125
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BMCBI
2008
110views more  BMCBI 2008»
15 years 3 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
126
Voted
BMCBI
2006
159views more  BMCBI 2006»
15 years 3 months ago
EpiJen: a server for multistep T cell epitope prediction
Background: The main processing pathway for MHC class I ligands involves degradation of proteins by the proteasome, followed by transport of products by the transporter associated...
Irini A. Doytchinova, Pingping Guan, Darren R. Flo...
109
Voted
BMCBI
2006
87views more  BMCBI 2006»
15 years 3 months ago
Prediction of indirect interactions in proteins
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
Peteris Prusis, Staffan Uhlén, Ramona Petro...
BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
108
Voted
BMCBI
2007
119views more  BMCBI 2007»
15 years 3 months ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...