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BMCBI
2006
130views more  BMCBI 2006»
15 years 4 months ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
BMCBI
2006
174views more  BMCBI 2006»
15 years 4 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
CLEIEJ
2006
97views more  CLEIEJ 2006»
15 years 4 months ago
Prediction of RNA Pseudoknotted Secondary Structure using Stochastic Context Free Grammars (SCFG)
Pseudoknots are a frequent RNA structure that assumes essential roles for varied biocatalyst cell's functions. One of the most challenging fields in bioinformatics is the pre...
Rafael Garcia
BMCBI
2007
113views more  BMCBI 2007»
15 years 4 months ago
Analysis and prediction of antibacterial peptides
Background: Antibacterial peptides are important components of the innate immune system, used by the host to protect itself from different types of pathogenic bacteria. Over the l...
Sneh Lata, B. K. Sharma, G. P. S. Raghava
BMCBI
2007
141views more  BMCBI 2007»
15 years 4 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...