A novel method to model and predict the location and orientation of alpha helices in membrane- spanning proteins is presented. It is based on a hidden Markov model (HMM) with an a...
Erik L. L. Sonnhammer, Gunnar von Heijne, Anders K...
Despite impressive advances in file system throughput resulting from technologies such as high-bandwidth networks and disk arrays, file system latency has not improved and in many...
A central problem in artificial intelligence is to choose actions to maximize reward in a partially observable, uncertain environment. To do so, we must learn an accurate model of ...
While John Holland has always envisioned learning classifier systems (LCSs) as cognitive systems, most work on LCSs has focused on classification, datamining, and function appro...
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...