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UM
2005
Springer
15 years 5 months ago
Modeling Individual and Collaborative Problem Solving in Medical Problem-Based Learning
Abstract. Since problem solving in group problem-based learning is a collaborative process, modeling individuals and the group is necessary if we wish to develop an intelligent tut...
Siriwan Suebnukarn, Peter Haddawy
BMCBI
2005
108views more  BMCBI 2005»
14 years 11 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
90
Voted
BMCBI
2006
87views more  BMCBI 2006»
14 years 11 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2008
80views more  BMCBI 2008»
14 years 11 months ago
Computational evaluation of TIS annotation for prokaryotic genomes
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
Gang-Qing Hu, Xiaobin Zheng, Li-Ning Ju, Huaiqiu Z...
BMCBI
2007
167views more  BMCBI 2007»
14 years 11 months ago
A stochastic differential equation model for transcriptional regulatory networks
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Adriana Climescu-Haulica, Michelle D. Quirk