Background: Evolutionary conservation has been used successfully to help identify cis-acting DNA regions that are important in regulating tissue-specific gene expression. Motivate...
Xueping Yu, Jimmy J. Lin, Donald J. Zack, Jiang Qi...
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
We introduce a novel data mining technique for the analysis of gene expression. Gene expression is the effective production of the protein that a gene encodes. We focus on the cha...
Aleksandar Icev, Carolina Ruiz, Elizabeth F. Ryder
Background: This work addresses the problem of detecting conserved transcription factor binding sites and in general regulatory regions through the analysis of sequences from homo...
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...