667 search results - page 25 / 134 » Predicting protein function from domain content |
GCB
2005
Springer
15 years 3 months ago
2005
Springer
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
106
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BMCBI
2004
14 years 9 months ago
2004
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
100
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ISBRA
2007
Springer
15 years 3 months ago
2007
Springer
Proteins are large organic compounds made of amino acids arranged in a linear chain (primary structure). Most proteins fold into unique threedimensional (3D) structures called inte...
BMCBI
2006
14 years 9 months ago
2006
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
109
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BMCBI
2008
14 years 9 months ago
2008
Background: Protein-protein interactions are ubiquitous and essential for all cellular processes. High-resolution X-ray crystallographic structures of protein complexes can reveal...