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» Predicting protein function from domain content
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PCI
2005
Springer
15 years 11 months ago
Protein Classification with Multiple Algorithms
Nowadays, the number of protein sequences being stored in central protein databases from labs all over the world is constantly increasing. From these proteins only a fraction has b...
Sotiris Diplaris, Grigorios Tsoumakas, Pericles A....
EVOW
2010
Springer
15 years 8 months ago
Improving Multi-Relief for Detecting Specificity Residues from Multiple Sequence Alignments
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
Elena Marchiori
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
15 years 11 months ago
Multi-Scale Hierarchical Structure Prediction of Helical Transmembrane Proteins
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Zhong Chen, Ying Xu
BMCBI
2008
178views more  BMCBI 2008»
15 years 5 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
JCB
2000
107views more  JCB 2000»
15 years 5 months ago
A Discriminative Framework for Detecting Remote Protein Homologies
A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
Tommi Jaakkola, Mark Diekhans, David Haussler