Sciweavers

667 search results - page 51 / 134
» Predicting protein function from domain content
Sort
View
CSB
2004
IEEE
106views Bioinformatics» more  CSB 2004»
15 years 9 months ago
Positive Sample Only Learning (PSOL) for Predicting RNA Genes in E. coli
RNA genes lack most of the signals used for protein gene identification. A major shortcoming of previous discriminative methods to distinguish functional RNA (fRNA) genes from oth...
Richard F. Meraz, Xiaofeng He, Chris H. Q. Ding, S...
BMCBI
2010
174views more  BMCBI 2010»
15 years 5 months ago
The effect of prior assumptions over the weights in BayesPI with application to study protein-DNA interactions from ChIP-based h
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
Junbai Wang
APBC
2004
116views Bioinformatics» more  APBC 2004»
15 years 6 months ago
Structure-Function Relationship in DNA Sequence Recognition by Transcription Factors
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...
Akinori Sarai, Samuel Selvaraj, M. Michael Gromiha...
BMCBI
2008
94views more  BMCBI 2008»
15 years 5 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
APBC
2004
166views Bioinformatics» more  APBC 2004»
15 years 6 months ago
THEMATICS is Effective for Active Site Prediction in Comparative Model Structures
THEMATICS (Theoretical Microscopic Titration Curves) is a simple, reliable computational predictor of the active sites of enzymes from structure. Our method, based on well-establi...
Ihsan A. Shehadi, Alper Uzun, Leonel F. Murga, Val...