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» Predicting protein function from domain content
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AIME
2007
Springer
15 years 11 months ago
Predictive Modeling of fMRI Brain States Using Functional Canonical Correlation Analysis
We present a novel method for predictive modeling of human brain states from functional neuroimaging (fMRI) data. Extending the traditional canonical correlation analysis of discre...
Sennay Ghebreab, Arnold W. M. Smeulders, Pieter W....
NAR
2008
152views more  NAR 2008»
15 years 5 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
BIBM
2008
IEEE
125views Bioinformatics» more  BIBM 2008»
15 years 5 months ago
Systems Biology via Redescription and Ontologies (III): Protein Classification Using Malaria Parasite's Temporal Transcriptomic
This paper addresses the protein classification problem, and explores how its accuracy can be improved by using information from time-course gene expression data. The methods are ...
Antonina Mitrofanova, Samantha Kleinberg, Jane Car...
BMCBI
2008
83views more  BMCBI 2008»
15 years 5 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
194
Voted
BMCBI
2007
127views more  BMCBI 2007»
15 years 5 months ago
Predicting the phenotypic effects of non-synonymous single nucleotide polymorphisms based on support vector machines
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
Jian Tian, Ningfeng Wu, Xuexia Guo, Jun Guo, Juhua...