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» Predicting protein function from domain content
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BMCBI
2004
141views more  BMCBI 2004»
15 years 5 months ago
Estimates of statistical significance for comparison of individual positions in multiple sequence alignments
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...
Ruslan Sadreyev, Nick V. Grishin
BMCBI
2007
143views more  BMCBI 2007»
15 years 5 months ago
RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules
Background: In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular ...
Yair Horesh, Tirza Doniger, Shulamit Michaeli, Ron...
123
Voted
BMCBI
2005
79views more  BMCBI 2005»
15 years 5 months ago
Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomes
Background: Cyclic nucleotides are ubiquitous intracellular messengers. Until recently, the roles of cyclic nucleotides in plant cells have proven difficult to uncover. With an un...
Dave Bridges, Marie E. Fraser, Greg B. G. Moorhead
158
Voted
ISMB
1994
15 years 7 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
RECOMB
2001
Springer
15 years 10 months ago
Extracting structural information using time-frequency analysis of protein NMR data
High-throughput, data-directed computational protocols for Structural Genomics (or Proteomics) are required in order to evaluate the protein products of genes for structure and fu...
Christopher James Langmead, Bruce Randall Donald