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» Predicting protein function from domain content
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149
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BMCBI
2010
119views more  BMCBI 2010»
15 years 5 months ago
Multi-task learning for cross-platform siRNA efficacy prediction: an in-silico study
Background: Gene silencing using exogenous small interfering RNAs (siRNAs) is now a widespread molecular tool for gene functional study and new-drug target identification. The key...
Qi Liu, Qian Xu, Vincent Wenchen Zheng, Hong Xue, ...
164
Voted
BMCBI
2008
146views more  BMCBI 2008»
15 years 5 months ago
nGASP - the nematode genome annotation assessment project
Background: While the C. elegans genome is extensively annotated, relatively little information is available for other Caenorhabditis species. The nematode genome annotation asses...
Avril Coghlan, Tristan J. Fiedler, Sheldon J. McKa...
137
Voted
JCP
2008
121views more  JCP 2008»
15 years 5 months ago
Towards Design Space Exploration for Biological Systems
For both embedded systems and biological cell systems, design is a feature that defines their identity. The assembly of different components in designs of both systems can vary wid...
Simon Polstra, Tessa E. Pronk, Andy D. Pimentel, T...
EMNLP
2010
15 years 3 months ago
Identifying Functional Relations in Web Text
Determining whether a textual phrase denotes a functional relation (i.e., a relation that maps each domain element to a unique range element) is useful for numerous NLP tasks such...
Thomas Lin, Mausam, Oren Etzioni
BIOINFORMATICS
2006
129views more  BIOINFORMATICS 2006»
15 years 5 months ago
Predicting methylation status of CpG islands in the human brain
Motivation: Over 50% of human genes contain CpG islands in their 5'-regions. Methylation patterns of CpG islands are involved in tissue-specific gene expression and regulatio...
Fang Fang, Shicai Fan, Xuegong Zhang, Michael Q. Z...