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» Predicting protein functions with message passing algorithms
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BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
ProFAT: a web-based tool for the functional annotation of protein sequences
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
Charles Richard Bradshaw, Vineeth Surendranath, Bi...
86
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NAR
2010
107views more  NAR 2010»
14 years 4 months ago
NAPS: a residue-level nucleic acid-binding prediction server
Nucleic acid-binding proteins are involved in a great number of cellular processes. Understanding the mechanisms underlying these proteins first requires the identification of spe...
Matthew B. Carson, Robert E. Langlois, Hui Lu
CDES
2006
97views Hardware» more  CDES 2006»
14 years 11 months ago
Protein Secondary Structure Prediction Accuracy versus Reduction Methods
Predicting protein secondary structure is a key step in determining the 3D structure of a protein that determines its function. The Dictionary of Secondary Structure of Proteins (...
Saad Osman Abdalla Subair, Safaai Deris
BMCBI
2006
111views more  BMCBI 2006»
14 years 9 months ago
PepDist: A New Framework for Protein-Peptide Binding Prediction based on Learning Peptide Distance Functions
Background: Many different aspects of cellular signalling, trafficking and targeting mechanisms are mediated by interactions between proteins and peptides. Representative examples...
Tomer Hertz, Chen Yanover