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» Predicting protein functions with message passing algorithms
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SDM
2011
SIAM
198views Data Mining» more  SDM 2011»
14 years 13 days ago
Exemplar-based Robust Coherent Biclustering
The biclustering, co-clustering, or subspace clustering problem involves simultaneously grouping the rows and columns of a data matrix to uncover biclusters or sub-matrices of the...
Kewei Tu, Xixiu Ouyang, Dingyi Han, Vasant Honavar
BMCBI
2010
99views more  BMCBI 2010»
14 years 9 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
14 years 9 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
NIPS
2008
14 years 11 months ago
Tighter Bounds for Structured Estimation
Large-margin structured estimation methods minimize a convex upper bound of loss functions. While they allow for efficient optimization algorithms, these convex formulations are n...
Olivier Chapelle, Chuong B. Do, Quoc V. Le, Alexan...
BMCBI
2010
113views more  BMCBI 2010»
14 years 9 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...