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99
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BMCBI
2010
102views more  BMCBI 2010»
14 years 5 months ago
Predicting protein-protein interactions in unbalanced data using the primary structure of proteins
Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles ...
Chi-Yuan Yu, Lih-Ching Chou, Darby Tien-Hao Chang
71
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NIPS
2004
14 years 11 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
100
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CSB
2002
IEEE
230views Bioinformatics» more  CSB 2002»
15 years 3 months ago
Prediction of Protein Function Using Protein-Protein Interaction Data
Assigning functions to novel proteins is one of the most important problems in the post-genomic era. Several approaches have been applied to this problem, including analyzing gene...
Minghua Deng, Kui Zhang, Shipra Mehta, Ting Chen, ...
ENGL
2008
121views more  ENGL 2008»
14 years 10 months ago
Prediction of Protein-Protein Interactions Using Pairwise Alignment and Inter-Domain Linker Region
One of the central problems in modern biology is to identify the complete set of interactions among the proteins in a cell. The structural interaction of proteins and their domains...
Nazar Zaki
111
Voted
RECOMB
2006
Springer
15 years 10 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...