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126
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
123
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: Cross-validation (CV) is an effective method for estimating the prediction error of a classifier. Some recent articles have proposed methods for optimizing classifiers...
149
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
144
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...
127
Voted
BMCBI
2007
15 years 3 months ago
2007
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...