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BMCBI
2007
143views more  BMCBI 2007»
14 years 10 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2005
132views more  BMCBI 2005»
14 years 10 months ago
Correlation and prediction of gene expression level from amino acid and dipeptide composition of its protein
Background: A large number of papers have been published on analysis of microarray data with particular emphasis on normalization of data, detection of differentially expressed ge...
Gajendra P. S. Raghava, Joon H. Han
BMCBI
2006
119views more  BMCBI 2006»
14 years 10 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2002
101views more  BMCBI 2002»
14 years 10 months ago
Match-Only Integral Distribution (MOID) Algorithm for high-density oligonucleotide array analysis
Background: High-density oligonucleotide arrays have become a valuable tool for highthroughput gene expression profiling. Increasing the array information density and improving th...
Yingyao Zhou, Ruben Abagyan
NAR
2006
142views more  NAR 2006»
14 years 10 months ago
miRNAMap: genomic maps of microRNA genes and their target genes in mammalian genomes
Recent work has demonstrated that microRNAs (miRNAs) are involved in critical biological processes by suppressing the translation of coding genes. This work develops an integrated...
Paul Wei-Che Hsu, Hsien-Da Huang, Sheng-Da Hsu, Li...