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BIBE
2003
IEEE
121views Bioinformatics» more  BIBE 2003»
15 years 5 months ago
Time Series Analysis of Gene Expression and Location Data
We develop a method for integrating time series expression profiles and factor-gene binding data to quantify dynamic aspects of gene regulation. We estimate latencies for transcr...
Chen-Hsiang Yeang, Tommi Jaakkola
BMCBI
2006
92views more  BMCBI 2006»
14 years 12 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
BMCBI
2007
144views more  BMCBI 2007»
14 years 11 months ago
Spectral estimation in unevenly sampled space of periodically expressed microarray time series data
Background: Periodogram analysis of time-series is widespread in biology. A new challenge for analyzing the microarray time series data is to identify genes that are periodically ...
Alan Wee-Chung Liew, Jun Xian, Shuanhu Wu, David K...
BMCBI
2002
195views more  BMCBI 2002»
14 years 11 months ago
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
Background: A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expressio...
Junbai Wang, Jan Delabie, Hans Christian Aasheim, ...
BMCBI
2006
116views more  BMCBI 2006»
14 years 12 months ago
Cluster analysis for DNA methylation profiles having a detection threshold
Background: DNA methylation, a molecular feature used to investigate tumor heterogeneity, can be measured on many genomic regions using the MethyLight technology. Due to the combi...
Paul Marjoram, Jing Chang, Peter W. Laird, Kimberl...