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BMCBI
2007
179views more  BMCBI 2007»
14 years 12 months ago
Transcript-level annotation of Affymetrix probesets improves the interpretation of gene expression data
Background: The wide use of Affymetrix microarray in broadened fields of biological research has made the probeset annotation an important issue. Standard Affymetrix probeset anno...
Hui Yu, Feng Wang, Kang Tu, Lu Xie, Yuan-Yuan Li, ...
BMCBI
2007
166views more  BMCBI 2007»
14 years 12 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
BMCBI
2008
124views more  BMCBI 2008»
14 years 12 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
KES
2005
Springer
15 years 5 months ago
Bayesian Validation of Fuzzy Clustering for Analysis of Yeast Cell Cycle Data
Clustering for the analysis of the gene expression profiles has been used for identifying the functions of the genes and of unknown genes. Since the genes usually belong to multipl...
Kyung-Joong Kim, Si-Ho Yoo, Sung-Bae Cho
BMCBI
2006
82views more  BMCBI 2006»
14 years 12 months ago
Selection of antisense oligonucleotides based on multiple predicted target mRNA structures
Background: Local structures of target mRNAs play a significant role in determining the efficacies of antisense oligonucleotides (ODNs), but some structure-based target site selec...
Xiaochen Bo, Shaoke Lou, Daochun Sun, Wenjie Shu, ...