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BMCBI
2010
106views more  BMCBI 2010»
14 years 12 months ago
A computational evaluation of over-representation of regulatory motifs in the promoter regions of differentially expressed genes
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Guofeng Meng, Axel Mosig, Martin Vingron
ICTAI
2007
IEEE
15 years 6 months ago
Accurate Classification of SAGE Data Based on Frequent Patterns of Gene Expression
In this paper we present a method for classifying accurately SAGE (Serial Analysis of Gene Expression) data. The high dimensionality of the data, namely the large number of featur...
George Tzanis, Ioannis P. Vlahavas
BMCBI
2005
148views more  BMCBI 2005»
14 years 11 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
BIBM
2008
IEEE
108views Bioinformatics» more  BIBM 2008»
15 years 6 months ago
Systematic Evaluation of Scaling Methods for Gene Expression Data
Even after an experimentally prepared gene expression data set has been pre-processed to account for variations in the microarray technology, there may be inconsistencies between ...
Gaurav Pandey, Lakshmi Naarayanan Ramakrishnan, Mi...
BMCBI
2007
134views more  BMCBI 2007»
14 years 12 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...