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BMCBI
2010
136views more  BMCBI 2010»
14 years 10 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BMCBI
2007
120views more  BMCBI 2007»
14 years 10 months ago
Computational analyses of eukaryotic promoters
Computational analysis of eukaryotic promoters is one of the most difficult problems in computational genomics and is essential for understanding gene expression profiles and reve...
Michael Q. Zhang
72
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BMCBI
2006
82views more  BMCBI 2006»
14 years 10 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
NAR
2010
189views more  NAR 2010»
14 years 4 months ago
Serial Expression Analysis: a web tool for the analysis of serial gene expression data
Serial transcriptomics experiments investigate the dynamics of gene expression changes associated with a quantitative variable such as time or dosage. The statistical analysis of ...
María José Nueda, José Carbon...
BMCBI
2004
115views more  BMCBI 2004»
14 years 10 months ago
Quantifying the relationship between co-expression, co-regulation and gene function
Background: It is thought that genes with similar patterns of mRNA expression and genes with similar functions are likely to be regulated via the same mechanisms. It has been diff...
Dominic J. Allocco, Isaac S. Kohane, Atul J. Butte