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114
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BMCBI
2002
214views more  BMCBI 2002»
14 years 10 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2004
100views more  BMCBI 2004»
14 years 10 months ago
Handling multiple testing while interpreting microarrays with the Gene Ontology Database
Background: The development of software tools that analyze microarray data in the context of genetic knowledgebases is being pursued by multiple research groups using different me...
Michael V. Osier, Hongyu Zhao, Kei-Hoi Cheung
RECOMB
2001
Springer
15 years 10 months ago
Analysis techniques for microarray time-series data
We address possible limitations of publicly available data sets of yeast gene expression. We study the predictability of known regulators via time-series analysis, and show that l...
Vladimir Filkov, Steven Skiena, Jizu Zhi
90
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BMCBI
2007
133views more  BMCBI 2007»
14 years 10 months ago
GenMAPP 2: new features and resources for pathway analysis
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
Nathan Salomonis, Kristina Hanspers, Alexander C. ...
NIPS
2000
14 years 11 months ago
Stability and Noise in Biochemical Switches
Many processes in biology, from the regulation of gene expression in bacteria to memory in the brain, involve switches constructed from networks of biochemical reactions. Crucial ...
William Bialek