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» Prediction of epigenetically regulated genes in breast cance...
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BMCBI
2010
109views more  BMCBI 2010»
14 years 12 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
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BMCBI
2006
123views more  BMCBI 2006»
14 years 11 months ago
Characterizing disease states from topological properties of transcriptional regulatory networks
Background: High throughput gene expression experiments yield large amounts of data that can augment our understanding of disease processes, in addition to classifying samples. He...
David Tuck, Harriet Kluger, Yuval Kluger