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» Prediction of indirect interactions in proteins
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RECOMB
2005
Springer
15 years 7 months ago
Examination of the tRNA Adaptation Index as a Predictor of Protein Expression Levels
Phenotypic differences between closely-related species may arise from differential expression regimes, rather than different gene complements. Knowledge of cellular protein levels ...
Orna Man, Joel L. Sussman, Yitzhak Pilpel
JCB
2006
215views more  JCB 2006»
15 years 1 months ago
Protein Fold Recognition Using Segmentation Conditional Random Fields (SCRFs)
Protein fold recognition is an important step towards understanding protein three-dimensional structures and their functions. A conditional graphical model, i.e., segmentation con...
Yan Liu 0002, Jaime G. Carbonell, Peter Weigele, V...
JCB
2000
146views more  JCB 2000»
15 years 1 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag
BMCBI
2008
94views more  BMCBI 2008»
15 years 2 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
BMCBI
2007
216views more  BMCBI 2007»
15 years 1 months ago
A replica exchange Monte Carlo algorithm for protein folding in the HP model
Background: The ab initio protein folding problem consists of predicting protein tertiary structure from a given amino acid sequence by minimizing an energy function; it is one of...
Chris Thachuk, Alena Shmygelska, Holger H. Hoos