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» Prediction of indirect interactions in proteins
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JCC
2011
154views more  JCC 2011»
14 years 4 months ago
Can we trust docking results? Evaluation of seven commonly used programs on PDBbind database
: Docking is one of the most commonly used techniques in drug design. It is used for both identifying correct poses of a ligand in the binding site of a protein as well as for the ...
Dariusz Plewczynski, Michal Lazniewski, Rafal Augu...
93
Voted
BMCBI
2007
113views more  BMCBI 2007»
15 years 2 months ago
Hinge Atlas: relating protein sequence to sites of structural flexibility
Background: Relating features of protein sequences to structural hinges is important for identifying domain boundaries, understanding structure-function relationships, and designi...
Samuel Flores, Long J. Lu, Julie Yang, Nicholas Ca...
KDD
2003
ACM
190views Data Mining» more  KDD 2003»
16 years 2 months ago
Distance-enhanced association rules for gene expression
We introduce a novel data mining technique for the analysis of gene expression. Gene expression is the effective production of the protein that a gene encodes. We focus on the cha...
Aleksandar Icev, Carolina Ruiz, Elizabeth F. Ryder
126
Voted
IUI
2003
ACM
15 years 7 months ago
Towards more conversational and collaborative recommender systems
Current recommender systems, based on collaborative filtering, implement a rather limited model of interaction. These systems intelligently elicit information from a user only dur...
Giuseppe Carenini, Jocelyin Smith, David Poole
130
Voted
BMCBI
2010
191views more  BMCBI 2010»
14 years 9 months ago
Molecular dynamics simulation studies and in vitro site directed mutagenesis of avian beta-defensin Apl_AvBD2
Background: Defensins comprise a group of antimicrobial peptides, widely recognized as important elements of the innate immune system in both animals and plants. Cationicity, rath...
Soja Saghar Soman, Krishnankutty Chandrika Sivakum...