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» Prediction of protein structural class with Rough Sets
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80
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MCS
2010
Springer
15 years 2 months ago
An Experimental Comparison of Hierarchical Bayes and True Path Rule Ensembles for Protein Function Prediction
Abstract. The computational genome-wide annotation of gene functions requires the prediction of hierarchically structured functional classes and can be formalized as a multiclass, ...
Matteo Re, Giorgio Valentini
BMCBI
2010
106views more  BMCBI 2010»
14 years 9 months ago
Predicting MHC class I epitopes in large datasets
Background: Experimental screening of large sets of peptides with respect to their MHC binding capabilities is still very demanding due to the large number of possible peptide seq...
Kirsten Roomp, Iris Antes, Thomas Lengauer
69
Voted
BMCBI
2004
150views more  BMCBI 2004»
14 years 9 months ago
Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs
Background: The wealth of information on protein structure has led to a variety of statistical analyses of the role played by individual amino acid types in the protein fold. In p...
Gareth Williams, Patrick Doherty
BMCBI
2007
63views more  BMCBI 2007»
14 years 9 months ago
Prediction of the burial status of transmembrane residues of helical membrane proteins
Background: Helical membrane proteins (HMPs) play a crucial role in diverse cellular processes, yet it still remains extremely difficult to determine their structures by experimen...
Yungki Park, Sikander Hayat, Volkhard Helms
BMCBI
2006
152views more  BMCBI 2006»
14 years 9 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...