367 search results - page 36 / 74 » Prediction of protein structural class with Rough Sets |
BIBM
2008
IEEE
15 years 4 months ago
2008
IEEE
Abstract—The exact relationship between protein active centers and protein functions is unclear even after decades of intensive study. To improve the functional prediction abilit...
DNA
2001
Springer
15 years 2 months ago
2001
Springer
The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
74
Voted
BMCBI
2006
2006
Searching for interpretable rules for disease mutations: a simulated annealing bump hunting strategy
14 years 9 months ago
Background: Understanding how amino acid substitutions affect protein functions is critical for the study of proteins and their implications in diseases. Although methods have bee...
JCB
2000
14 years 9 months ago
2000
A previously developed algorithmic method for identifying a geometric invariant of protein structures, termed geometrical core, is extended to the and 1 domains of immunoglobulin ...
BMCBI
2006
14 years 9 months ago
2006
Background: Measuring each protein's importance in signaling networks helps to identify the crucial proteins in a cellular process, find the fragile portion of the biology sy...