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BMCBI
2010
169views more  BMCBI 2010»
14 years 9 months ago
eCOMPAGT integrates mtDNA: import, validation and export of mitochondrial DNA profiles for population genetics, tumour dynamics
Background: Mitochondrial DNA (mtDNA) is widely being used for population genetics, forensic DNA fingerprinting and clinical disease association studies. The recent past has uncov...
Hansi Weißensteiner, Sebastian Schönher...
BMCBI
2010
155views more  BMCBI 2010»
14 years 9 months ago
BISMA - Fast and accurate bisulfite sequencing data analysis of individual clones from unique and repetitive sequences
Background: Bisulfite sequencing is a popular method to analyze DNA methylation patterns at high resolution. A region of interest is targeted by PCR and about 20-50 subcloned DNA ...
Christian Rohde, Yingying Zhang, Richard Reinhardt...
BMCBI
2008
153views more  BMCBI 2008»
14 years 9 months ago
2DB: a Proteomics database for storage, analysis, presentation, and retrieval of information from mass spectrometric experiments
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...
Jens Allmer, Sebastian Kuhlgert, Michael Hippler
TCBB
2008
93views more  TCBB 2008»
14 years 9 months ago
2SNP: Scalable Phasing Method for Trios and Unrelated Individuals
Emerging microarray technologies allow affordable typing of very long genome sequences. A key challenge in analyzing of such huge amount of data is scalable and accurate computatio...
Dumitru Brinza, Alexander Zelikovsky
BMCBI
2010
113views more  BMCBI 2010»
14 years 9 months ago
Probabilistic Principal Component Analysis for Metabolomic Data
Background: Data from metabolomic studies are typically complex and high-dimensional. Principal component analysis (PCA) is currently the most widely used statistical technique fo...
Gift Nyamundanda, Lorraine Brennan, Isobel Claire ...