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BMCBI
2010
97views more  BMCBI 2010»
15 years 4 months ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
BMCBI
2007
83views more  BMCBI 2007»
15 years 4 months ago
Identification of sequence motifs significantly associated with antisense activity
Background: Predicting the suppression activity of antisense oligonucleotide sequences is the main goal of the rational design of nucleic acids. To create an effective predictive ...
Kyle A. McQuisten, Andrew S. Peek
NC
2008
15 years 4 months ago
How crystals that sense and respond to their environments could evolve
An enduring mystery in biology is how a physical entity simple enough to have arisen spontaneously could have evolved into the complex life seen on Earth today. Cairns-Smith has pr...
Rebecca Schulman, Erik Winfree
JCB
2007
130views more  JCB 2007»
15 years 4 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
ICML
2005
IEEE
16 years 5 months ago
Combining model-based and instance-based learning for first order regression
T ORDER REGRESSION (EXTENDED ABSTRACT) Kurt Driessensa Saso Dzeroskib a Department of Computer Science, University of Waikato, Hamilton, New Zealand (kurtd@waikato.ac.nz) b Departm...
Kurt Driessens, Saso Dzeroski